Article

Gaussian Representation for Deformable Image Registration
Gaussian Representation for Deformable Image Registration

This paper presented a novel deformable image registration (DIR) technique using parametric 3D Gaussian control points to model continuous spatial deformation fields effectively. By integrating transformation vectors with linear blend skinning (LBS) for voxel motion interpolation, our approach simplifies computational demands while ensuring high accuracy and efficiency. The adaptive density of Gaussian points further allows for precise handling of varying motion complexities.

Nov 9, 2024

CPT-Interp: Continuous sPatial and Temporal Motion Modeling for 4D Medical Image Interpolation
CPT-Interp: Continuous sPatial and Temporal Motion Modeling for 4D Medical Image Interpolation

In this work, we introduce a novel Continuous sPatial and Temporal (CPT) modeling approach for 4D medical image interpolation, addressing the limitations of discrete motion modeling in both spatial and temporal domains. By leveraging implicit neural representations and integrating an ODE solver, our method achieves superior accuracy and speed without requiring extensive training datasets or domain-specific fine-tuning. Through comprehensive experiments and ablation studies, we demonstrated the contributions of spatial and temporal continuity, as well as the robustness of our method across different datasets. CPT-Interp not only outperforms state-of-the-art methods but also exhibits remarkable generalization ability, making it a promising solution for clinical applications.

Nov 9, 2024

TAMBRIDGE: Bridging Frame-Centered Tracking and 3D Gaussian Splatting for Enhanced SLAM
TAMBRIDGE: Bridging Frame-Centered Tracking and 3D Gaussian Splatting for Enhanced SLAM

Our goal was to develop a 3DGS-based SLAM system suitable for intelligent robotic perception tasks. The system is designed to meet the real-time requirements of robotic perception, and is robust against random sensor noise, motion blur and challenges posed by long-session SLAM. To achieve this, we have implemented a plug-and-play Fusion Bridge module that filters redundant views and leverages the anchoring effect of reprojection errors to estimate poses for rendering initially. This approach marks the first integration of a tracking-centered paradigm with an ORB-based visual odometry frontend together with a 3DGS-centered backend. Our system consistently achieves realtime localization and near-real-time rendering at over 5 FPS on the real-world TUM RGB-D dataset. Furthermore, it significantly surpasses SplaTAM in localization accuracy, rendering quality, and robustness in scenarios involving motion blur and long-distance SLAM tasks

May 30, 2024

Beyond Voxel-Based Methods: Continuous Motion Modeling for Enhanced Deformable Image Registration
Beyond Voxel-Based Methods: Continuous Motion Modeling for Enhanced Deformable Image Registration

Our novel approach, capitalizing on the power of INR, offers a means to model motion in a continuous manner for intra-fraction motion modelling. By representing the registration process as a continuous flow, we circumvent the limitations inherent to the classic voxel-based representations, particularly the dilemma of discretization. The tangible enhancements are evident: both INR-DIR (E2E and LDD) methods consistently outperformed classic B-splines regarding TRE, MAE, landmark, and Dice coefficients. Remarkably, the registration times were slashed by more than half. One of the standout features of our LDD method is its ability to handle reverse trajectories, a capability unattainable with prior techniques. This promises more robust and versatile image registration applications in radiotherapy.

May 3, 2024

Continuous sPatial-Temporal Deformable Image Registration (CPT-DIR) for motion modelling in radiotherapy: beyond classic voxel-based methods
Continuous sPatial-Temporal Deformable Image Registration (CPT-DIR) for motion modelling in radiotherapy: beyond classic voxel-based methods

In summary, the innovative CPT-DIR approach, integrating principles of INR and LDDMM, represents a11 significant departure from traditional voxel-based methods in DIR. By adopting a paradigm of continuous motion modelling, we transcend the limitations inherent in voxel-based representations, offering a more robust, automatic and versatile solution. Leveraging spatial continuity, we effectively handle the intricacies of sliding organ boundaries, while temporal continuity alleviates the complexities associated with significant anatomical changes over time. The tangible benefits are evident in its superior performance compared to classic B-splines methods. CPT-DIR consistently achieves better performance by all kinds of evaluation matrices. Additionally, the efficiency gains are substantial, with registration times slashed by more than half.

May 1, 2024

Uncertainty-Aware Testing-Time Optimization for 3D Human Pose Estimation
Uncertainty-Aware Testing-Time Optimization for 3D Human Pose Estimation

In this paper, we propose an Uncertainty-Aware testing-time Optimization (UAO) framework for 3D human pose estimation. During the training process, we propose the GUMLP to estimate 3D results and uncertainty values for each joint. For test-time optimization, our UAO framework freezes the pre-trained network parameters and optimizes a latent state initialized by the input 2D pose. To constrain the optimization direction in both 2D and 3D spaces, projection and uncertainty constraints are applied. Extensive experiments show that our approach achieves state-of-the-art performance on two popular datasets

Feb 15, 2024

A Unified Generation-Registration Framework for Improved MR-based CT Synthesis in Proton Therapy
A Unified Generation-Registration Framework for Improved MR-based CT Synthesis in Proton Therapy

In this study, we developed an approach that substantially improves the anatomical accuracy of synthetic CT (sCT) images for MR-based radiotherapy planning. By integrating image generation with the deformable registration processes, the novel framework effectively addresses the inherent challenges in MR-CT registration and sCT evaluation. The methodological synergy of generation and registration networks, coupled with a strategic approach to proton dose planning, contributes to enhancing treatment planning accuracy. This study represents a meaningful step forward in the application of MR-based proton treatment planning and daily adaptive replanning, offering potential improvements in reducing the imaging-related dose and patient outcomes in the field of radiotherapy.

Jan 20, 2024