Neural Graphics Primitives-based Deformable Image Registration for On-the-fly Motion Extraction

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Abstract

Intra-fraction motion in radiotherapy is commonly modeled using deformable image registration (DIR). However, existing methods often struggle to balance speed and accuracy, limiting their applicability in clinical scenarios. This study introduces a novel approach that harnesses Neural Graphics Primitives (NGP) to optimize the displacement vector field (DVF). Our method leverages learned primitives, processed as splats, and interpolates within space using a shallow neural network. Uniquely, it enables self-supervised optimization at an ultra-fast speed, negating the need for pre-training on extensive datasets and allowing seamless adaptation to new cases. We validated this approach on the 4D-CT lung dataset DIR-lab, achieving a target registration error (TRE) of 1.15±1.15 mm within a remarkable time of 1.77 seconds. Notably, our method also addresses the sliding boundary problem, a common challenge in conventional DIR methods.

Publication
International Conference on the use of Computers in Radiation therapy
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Xia Li
Xia Li
Doctoral Students
Muheng Li
Muheng Li
Doctoral Students
Damien Weber
Damien Weber
Prof. Dr. med.
Tony Lomax
Tony Lomax
Professor
Ye Zhang
Ye Zhang
Research Scientist